| TOLOS VIP SECURITY Pty Ltd | Johannesburg | Security Guards-VIP Shuttles-Event Security | |
| Social Enterprises Management Accountants | Johannesburg | Small Business Consulting and Accounting | |
| Zania Group | Bloemfontein | Business Development Solutions | |
| Silver Cloud Accounting | Cape Town | Accounting, Payroll & Business Advisory Services | |
| Rosy's Event Design and Decor | Cape Town | Events Decor and Design | |
| Viatron Cleaning Services (Pty) Ltd | Cape Town | Cleaning services public, private sector entities | |
| Simplify Recruitment Services | Pretoria | Recruitment of staff | |
| Sandton Taxi Cabs | Sandton | Staff Transport, Airport Transfers,Shuttle Service | |
| True Wealth Solutions | Durban | Financial advisory services | |
| S Packery Chartered Accountants | Nelspruit | Audit Firm | |
| Soil Poisoning Services | Warden | Soil Poisoning Services | |
| RSA Catering | Johannesburg | Catering Services, Caterer | |
| Simpson Accounting (Pty) Ltd | Randburg | Accounting Services | |
| TS Translations CC t/a Perfect Language | Johannesburg | Translations | |
| The Best Private Investigator Cape Town | Cape Town | Private Investigations | |
| Tri Wealth | Cape Town | Insurance | |
| Terabyte Website Design Pietermarizburg | Pietermaritzburg | Website Design and Online Marketing | |
| Tweak Group | Johannesburg | Transport | |
| Rolfe Auto Repair Services | Pretoria East | Mechanics | |
| Romaflo Travel | Newcastle | Travel Services. | |
| Rooihuiskraal Geyser Repairs | Pretoria | Plumbing Repairs | |
| Ropelius. Brand and Design | Cape Town | Branding and Packaging Design | |
| Rospa Transport & Services | Benoni | 91 Woburn Avenue,Benoni | |
| Royal Electronics Sales and Services | | Royal Electronics Sales and Services | |
| Royal Hairstyles Training Academy and Salon | Johannesburg | SETA-accredited hairdressing academy | |
| Royal Investigations | Cape Town | Cheating spouse, fraud, trace | |
| Rozewood | Pretoria | Managing agent, Sectional Title Homeowners Ass | |
| Ry Cin Group Shuttles Tors and Adventures | Cape Town | Airport shuttle service, Tours & group transport | |
| Ryder Consulting | Benoni | Business Consulting | |
| S.S Engineering Services | | S.S Engineering Services | |
| Safe House Services , . | Worthing | Plumbers | |
| Safety Connection KZN | Durban | Health and Safety Consulting and Compliance | |
| Sage Legal Services | Johannesburg | Legal and Consulting | |
| Saglotech Web Design | Johannesburg | Web Design | |
| Sakha Isizwe Engineering and Projects | Standerton | Electrical and mechanical mainteance | |
| Sakhona HR | Pretoria | Human Resources, Payroll, Recruitment | |
| Sales Hub for Africa | | Sales Solutions and Sales Outsourcing | |
| Saltyfm | Johannesburg | sound hire | |
| Salvagedata Recovery Services Mint Hill | Mint Hill | DATA Recovery Services | |
| Samantha Atrash, Fundraising and CSI | Edenglen | Fundraising, Corporate Social Investment | |
| Samplex Africa | Johannesburg | Field Sales Merchandising Brand Activations | |
| SANCSERV SECURITY SERVICES | Johannesburg | security services | |
| Sancserv Cleaning Services | Johannesburg | Cleaning Services | |
| Sandilands et al | Bedfordview | Compliance governance Payroll Accounting HR IR | |
| S&S Mechanical Services Inc | | HVAC | |
| SaniTate360 | Cape Town | Cleaning/Sanitizing-office,w/h,toilet,kitchen, etc | |
| SA TaG | Johannesburg | Business listing, marketing and advertising | |
| SA Teen Entrepreneur | Cape Town | Cultivate and promote entrepreneurial spirit | |
| Satrim Technologies | Durban | Web Solutions | |
| Scan4U Scanning Services | Modderfontein | Document scanning services and scanning bureau | |
| Weblab | Durban | Web Design, Website Design, Online Marketing, SEO | |
| SEA Hospitality Consultants (Pty) LTD | Port Elizabeth | Hospitality Consultant | |
| Seamless Events Solutions | Nairobi | Conferences and Corporate Events Management | |
| Sebashe consultants and Field marketers | Kempton park | Direct marketing | |
| Seed of Prosperity - Financial Wellness Experts | Johannesburg | Employee financial wellness for peak productivity | |
| Sekunjalo Group | Cape Town | Broadcasting and Media | |
| The Movement Trust | Cape Town | Film & TV Production | |
| SellRent Ghana | Spintex | Brokerage, Marketing, Property Management, Agents, | |
| Semipoi Online | | Semipoi Online Nonton Film Semi 2020 | |
| Sengikwenzile Supplier Services | Durban | Road Freight Logistics | |
| SeniNhle Occupational Health Services | Pretoria | Asbestos, risk assessment, noise, ergonomics, HCS | |
| SeniNhle Occupational Health Sevices | Pretoria | Occupational health and safety, risk, hygiene | |
| Sentinel Commercial Services Group | Cape Town | Business Sales and Valuations | |
| Sentinels Leak Detection Services | Johannesburg | Leak Detection on property plumbing systems. | |
| SEO Traffic | Cape Town | Search Engine Optimization, Local SEO, SEO Package | |
| Septic Tank Cleaning(PumpItUp Liquid Waste) | Midrand | Septic Tank Cleaning/Pumping | |
| ServeIT Data | | b2b email list providers | |
| Seta Accreditation Services | Ramsgate | Training Provide Accreditation, Skills Development | |
| Shipx | Randburg | Shipx logistics services | |
| Show TV | Johannesburg | Video, Photographic & Graphic Design Company | |
| Shubone Events | johannsburg | wedding and event planning,Hiring services,florist | |
| Shumba Connect | | telecommunications | |
| Shumu Protection Services | Cape Town | Security Guarding | |
| Sigmatilers | Cape Town | Tilers builders | |
| Signa Opportunity | Randburg | Youth Employment Services (YES) | |
| Signa Trust | Randburg | Female Student Support | |
| Signs360 | Johannesburg | Signage and Branding | |
| Silkmusic Wedding Djs | Cape Town | Wedding DJ | |
| Silver Linings Technologies | Pietermaritzburg | Website Design and SEO | |
| Silver Solutions T/A About Turn Logistics | Cape Towwn | International and Domestic Courier, Air Freight | |
| Silverworx Staffing Solutions | Umhlanga | catering, events, mobile bartenders, waiters | |
| SimpLee VA Services | | Virtual Assistant Services | |
| Sindicare Medical Suites | Durban | General Medical Services and Dental Services | |
| Singhs Attorneys | Johannesburg | Attorneys | |
| Singjohn.Com | | singjohn | |
| Sistersystems | Newcastle | ICT Solutions | |
| Siyembili Consulting & Business Services | | Research & Business Consulting | |
| SJC Creative | Randburg | media communications/writing/photography/pr | |
| Skankane Transport | Nelspruit | Break Bulk | |
| Skhandzia Construction and Services | Johannesburg | General construction work,Civil and maintenance | |
| SKT Cleaning Servcies | | cleaning & Maid services | |
| Skylight Digital | Cape Town | Digital Marketing | |
| Skytrax Accounting and Payroll Services | Johannesburg | Accounting and Payroll | |
| Slimber Services | lobatse | customs clearing and forwading | |
| slumREC | Maputsoe | Music production | |
| Smart Staff | Cape Town | Staff training & on-boarding via mobile | |
| Smart Money - Financial Experts | Johannesburg | Financial wellness | |
| Smit Computer Services | Tzaneen | Computer and Printer Support, Networking and sales | |
| SMSPortal | Cape Town | Bulk SMS Service | |
| SNK Consulting Logistics | Isando | LOGISTICS; SUPPLY CHAIN; DISTRIBUTION | |
